Effect of ileal infusion of glycochenodeoxycholic acid
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چکیده
cm jejunal segment proximal (n=6) and a 40 cm ileal segment distal (n=6) to a GCDC infusion port were measured. During GCDC infusion (60 pimoVmin) jejunal and ileal transit were markedly (p<005) delayed (31.6 (7.7), mean (SEM) v 14.5 (3.8) min and 37.0 (5.7) v 21-0 (3.5) min, respectively), segment volumes increased (141.1 (30.2) v 59.2 (9.9) ml and 173.2 (26.3) v 83.9 (9.5) ml; p<0 05), while flow rates did not change significantly (4.6 (0.6) v 4.5 (0.6) mImin and 4-8 (0.5) v 4.2 (0.3) mUmin, respectively). Ileal pressures (distal to the GCDC infusion port) decreased (p<005) promptly (1.0 (0.1) min) after the start of GCDC infusion. Inhibition of jejunal motility
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